Ketoprofen

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for the relief of pain and inflammation associated with musculoskeletal disorders, arthritis, and soft tissue injuries. It provides analgesic, anti-inflammatory, and antipyretic effects, making it useful in a variety of acute and chronic pain conditions. Ketoprofen is available in oral as well as topical formulations, allowing flexibility in clinical use.

The drug acts by inhibiting cyclooxygenase enzymes and reducing prostaglandin synthesis at sites of inflammation. This leads to decreased pain signaling, reduced tissue swelling, and improved functional mobility. Because of its effectiveness in musculoskeletal pain, ketoprofen is often used in conditions such as osteoarthritis, rheumatoid arthritis, sports injuries, and postoperative pain.

Ketoprofen dosing depends on the formulation and clinical indication, and it is generally recommended to use the lowest effective dose for the shortest duration necessary. Taking the medication with food may help reduce gastrointestinal discomfort.

Potential side effects include dyspepsia, nausea, and gastric irritation. Like other NSAIDs, prolonged use may increase the risk of gastrointestinal bleeding or renal effects in susceptible patients. Careful use under medical guidance helps optimize safety. When used appropriately, ketoprofen remains an effective option for managing inflammatory and musculoskeletal pain.